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Apexa

46000 ֏
In stock

SHort description

Indications: . to improve ejaculate performance . to activate sperm motility, sperm metabolism and stimulate spermatogenesis . with teratozoospermia, oligozoospermia, asthenozoospermia . with oligoteratoasthenozoospermia . with a decrease in reproductive functions . in preparation for the use of reproductive technologies . after varicocele surgery Component Quantity% Content, mg Magnesium citrate 55,0 2750,0 L-carnitine tartrate 27,0 1350,0 L-arginine alpha-ketoglutarate 5,4 270,0 Vitamin E (DL-alpha-tocopherol 4,0 200,0 acetate) Fructose 2,9836 149,18 Zinc aspartate 2,2 110,0 Vitamin C 1,82 91,0 Coenzyme Q10 1,04 52,0 Flavor Orange identical to natural 0,25 12,5 Sucralose (E955) 0,08 4,0 Vitamin B2 (riboflavin) 0,062 3,1 Vitamin B12 (cyanocobalamin) 0,06 3,0 Sladin 200K (E952, E954) 0,05 2,5 Vitamin B6 (pyridoxine 0,042 2,1 hydrochloride) Folic acid 0,009 0,45 sodium selenite 0,0034 0,17 TOTAL: 100,0 5000,0

  • Description products
     APEXA
    "Apexa" 5g. N30 Powder / “Giga Farm” / Biologically Active
    Additive (BAA) to food
    Release form:
    Sachet by 5 g. - 30 pcs. in a pack.
    Description of the dosage form:
    Powder from light grayish-yellow to dark-grayish yellow color.
    Composition:
    One sachet contains the following: magnesium citrate, L-carnitine
    tartrate, L-arginine alpha ketoglutarate, vitamin E (DL alpha tocopherol
    acetate), fructose, zinc asparaginate, vitamin C, coenzyme Q10, orange
    aroma identical to natural flavor, sweetening sucralose, vitamin B2
    (riboflavin), vitamin B12 (cyanocobalamin), sweetening "Sladin 200K"
    (contains: sodium saccharinate, sodium cyclamate), vitamin B6 (pyridoxine
    hydrochloride), folic acid, sodium selenite.
    Description and properties
    Action of Apexa is determined by the properties of its active
    ingredients:
    1 L-carnitine tartrate:
     L-carnitine is a natural vitamin-like substance providing the entire
    spermatogenesis process with energy
     L-carnitine is found in high concentrations in the epididymis and plays an
    important role in metabolism and maturation of spermatozoa. It also
    affects spermatozoa mobility and is an antioxidant.
     Lack of L-carnitine in the body leads to a decrease in the cellular energy
    of spermatozoa, which significantly reduces the quality of sperm.
     The use of L-carnitine tartrate normalizes the balance of oxidation and
    anti-oxidation processes in sperm and its fertilizing ability.
     As a whole, the effect of carnitine on the indices of the routine
    spermogram is described in the literature, and in some cases its effects
    on the functional characteristics of the spermatozoa have been studied.
     The concentration of L-carnitine at men with oligoasthenozoospermia is
    reduced as compared with the fertile men.
     There is a significant positive correlation between LC level and the
    quantity of spermatozoa, as well as their mobility.
     Clinical trials have shown that carnitine improves spermatozoa
    parameters at men with astheno and oligozoospermia
     These observations, together with the firmly established role of L-
    Carnitine in the production of energy by spermatozoa, provide the
    scientific basis for the application of therapy for the treatment of many
    cases of male infertility.
     The improvement of indices of spermogram optimizes the forecast while
    conducting the auxiliary reproductive technologies. In addition, L-carnitine
    can be used in the prevention and treatment of secretory male infertility.
     Vitali et al. studied the effectiveness of the oral administration of 3 g of LC
    per day for 3 months for 47 patients [Vitali et al., 1995]
     Young age, infertility for at least 2 years, and idiopathic
    asthenozoospermia as a cause of infertility have been the criteria of
    inclusion in the given study.
     At the end of the therapeutic period, approximately 80% of patients
    experienced an increase in spermatozoa mobility to a level almost equal
    to the control group of 110 fertile donors and exceeding the lower WHO
    standard.
     The average quantity of spermatozoa increased by 44.6% and the
    average quantity of mobile spermatozoa increased by 99.6%
     A study has been conducted, whose purpose was to study the influence of
    carnitine on the physical indicators of the ejaculate, as well as the
    quantitative and functional characteristics of spermatozoa at men with
    the oligoasthenozoospermia and the male factor of infertility in marriage.
     60 patients with idiopathic pathospermia aged 23-35 years have been
    examined. The average age of patients in the group was 29.2 ± 0.8 years.
    All the surveyed have been in the infertile marriage from 1 year to 10
    years
     The conducted clinical study showed that L-carnitine in a form of tartrate
    normalizes the balance of pro- and antioxidant systems in the ejaculate.
    This leads not only to an improvement of ejaculate characteristics, but
    also to an approach of pregnancy at the wives of the studied patients
    (within 3 months of treatment, i.e., in the period during which the
    maturation of spermatozoa is fully completed, pregnancy occurred in 14
    (23%) patients).
    2 Zinc asparaginate:
     Zinc is responsible for the processes of growth and production of the male
    sex hormone – testosterone
     Zinc, as a biological component, is present in many organs, but its
    maximum content is found in spermatozoa (up to 2 mg of zinc per
    milliliter) and the prostate gland of men. This shows the great importance
    of zinc for spermatogenesis and the functioning of the prostate.
     Zinc deficiency threatens men with the following:
     sexual dysfunction
     reduction of sperm quality and infertility
     decrease in the synthesis of sex hormones (testosterone)
     Zinc is used in the clinical practice at the treatment of male infertility and in
    programs of auxiliary reproductive technologies.
    3 Sodium Selenite:
     Selenium is an indispensable element for the normal spermatogenesis
    and the provision of male fertility, regulates the functioning of the genital
    organs, participates in the synthesis of testosterone.
     Selenium is one of the main micro elements of the antioxidant system of
    the human body. Selenium is part of the catalytic center of the main
    enzyme of the antioxidant system of glutathione peroxidase, thereby
    ensuring the inactivation of active forms of oxygen that have a toxic
    effect on spermatozoa, reducing the qualitative indices of ejaculate.
     In addition, the active forms of oxygen that cause oxidative stress have a
    negative effect on endothelial cells. As a result conditions contributing to
    the development of erectile dysfunction appear.
     Selenium is a synergist of vitamin E, thereby enhancing its antioxidant
    activity.
     It is interesting that the activity of spermatozoa is greatly determined by
    the presence of a specific selenium-containing protein in the tail of the
    spermatozoon.
     Selenium has an antitumor effect and its lack may be a risk factor for the
    development of malignant tumors of the prostate gland, ovaries.
    4 Magnesium citrate:
     Magnesium refers to vital elements
     Magnesium increases fertilizing ability, as it increases the mobility of
    spermatozoa.
     Magnesium increases the quantity of bioactive (free) testosterones at the
    men
     An in vitro study showed that magnesium makes testosterone more
    bioactive. The mineral inhibits HSPG (globulin binding sex hormones),
    which binds to free testosterone, making it inaccessible to receptors and
    is, in fact, useless.
     Magnesium stimulates energy production, contributes to regulate the
    levels of vitamin D, potassium, calcium, copper and zinc.
     The lack of magnesium and zinc seriously decreases the level of
    testosterone.
    5 Vitamins C and E:
     The sufficient content of vitamins is necessary for the normal functioning
    of the organism and, in particular, the sexual system. Vitamins and micro
    elements with antioxidant activity are most important for the
    reproductive system of men (vitamin E and C)
     A group of scientists from the Harvard University found that four out of
    five couples who cannot conceive a child have a lack of vitamins C and E.
     Vitamin C directly affects sperm production and increases spermatozoa
    mobility, and can help prevent spermatozoa from sticking together (it is
    used to disagglutination of sperm in case of male infertility. Sperm
    agglutination is caused by the increased oxidation of a number of its
    proteins. In the presence of vitamin C, proteins are not oxidized,
    regenerate and spermatozoa are separated, the percent of normal
    spermatozoa increased, participate in the synthesis of testosterone,
    contributes to the improvement of the production of healthy spermatozoa.
     Vitamin E stimulates the sexual and reproductive function, has a positive
    effect on potency, improves sexual function, positively effect on
    hormones, prevents the damage of spermatozoa cells, accelerates the
    healing of damaged cellular structures, increases the number, mobility
    and vitality of spermatozoa.
    6 Vitamins B2 B6 B9 B12:
     The vitamins of group B increase testosterone synthesis, restore energy
    exchange, protect the liver, improve the functioning of the heart, the
    nervous system
     Vitamin B6 (pyridoxine) improves the activity and mobility of
    spermatozoa, contributes to the suppression of the production of the
    prolactin hormone, which is responsible for the increase of the volume of
    the prostate gland, the development of benign hyperplasia and disorder
    of reproductive functions. Vitamin B 6 is necessary for the synthesis of
    DNA and RNA. It participates in the proper absorption and metabolism of
    carnitine.
     Vitamin B9 (folic acid) participates in the formation of the structure of
    spermatozoa, controls their mobility and functionality, increases the
    volume of non-defective spermatozoa and the chances of conception.
     Vitamin B12 (cyanocobalamin) protects against the prostate cancer,
    increases the number and mobility of spermatozoa, improves the quality
    of sperm, is used for the solution of problems of infertility.
    7 L-arginine:
     Stimulates spermatogenesis and blood supply to the genitals
     Favorably effects on the health of the prostate gland, increases sperm
    production and increases blood flow to the genitals, creating conditions
    for more stable and prolonged erection.
     Seminal fluid consists of protein building material by 80%, so a lack of L-
    arginine can lead to infertility
    8 Fructose:
     is the main source of energy for ejaculated spermatozoa and improves the
    fertility properties of the ejaculate.
    9 Coenzyme Q10:
     Coenzyme Q10 has properties identical to vitamins, but due to the fact that
    it is synthesized by the body, it is not included in the number of vitamins.
    Most of all it is present in mitochondria and is involved in the most important
    chemical reactions.
     Coenzyme Q 10 is able to improve the quality of sperm and positively affects
    the kinetic characteristics of gametes
     Researches have shown that coenzyme Q10 is able to improve sperm
    density and quantity at the infertile men.
     The quality of sperm was associated with oxidative stress, and at the same
    time it was assessed what level of coenzyme Q 10 could favorably affect
    sperm quality. The research involved 212 infertile men, who were divided
    into two groups. One group took coenzyme Q 10 (300 mg, Kaneka, Japan),
    the second group took placebo for 26 weeks.
     An increase in spermatozoa density and an improvement in their motility has
    been noted. The effect on the sperm quantity was also positive. The
    subsequent analyzes showed an increase in the percentage of correct sperm
    forms. In the group treated with coenzyme Q 10, a significant, 100%
    increase in the acrosome reaction has been registered as compared with an
    increase of 1% in the group taking placebo. The acrosomal reaction helps the
    spermatozoon penetrate into the egg.
    Special instructions
    Before use, it is recommended to consult a doctor.
    Biologically active substance.
    Content
    mg / sachet.
    The daily use level in mg. Percentage from the level of daily use:
    L-carnitine 900 300.01 3003
    Coenzyme Q10 50 30.01 1673
    Vitamin E 100 10.02 10003
    Vitamin C 90 60.02 1503
    Vitamin B2 3 1.62 1883
    Vitamin B6 2 2.02 100
    Vitamin B12 0.003 0.0012 3003
    Folic acid 0.4 0.22 2003
    Magnesium 400 400.02 100
    Zinc 20 15.02 1333
    Selenium 0.075 0.072 1073
    1.An adequate level of the daily use according to the requirements of the
    Eurasian Economic Community (Annex 5).
    2 The recommended level of daily use in accordance with the requirements
    of ТР ТС 022 (Annex 2).
    3 Does not exceed the upper permissible level of daily use.
    Contraindications:
    Individual intolerance to the components, pregnancy, breast-feeding.
    Before use, it is recommended to consult a doctor.
    Method of administration
    To dissolve 5 g of powder (the contents of one pack of sachet) in 200
    ml of water. Adults should take by 200 ml of ready beverage 1 time per day
    during meals.
    Duration of use:
    1 month. If necessary, the taking can be repeated in 2-3 weeks.
    Storage conditions
    Should be stored in a dry, dark place and out of reach of children, at a
    temperature not exceeding 25 ° C and at relative air humidity not more than
    75%.
    Manufacturer
    Manufactured by the order: the “Giga Farm” LLC, tel: +37494000264;
    website: www. gigafarm.ru. Manufacturer: the “AlinaPharma” LLC, 142380,
    the Moscow oblast, Chekhovsky district, village Lyubuchany, the “Institute of
    Engineering Immunology” OJSC, building 3 (Russian Federation)
 APEXA
"Apexa" 5g. N30 Powder / “Giga Farm” / Biologically Active
Additive (BAA) to food
Release form:
Sachet by 5 g. - 30 pcs. in a pack.
Description of the dosage form:
Powder from light grayish-yellow to dark-grayish yellow color.
Composition:
One sachet contains the following: magnesium citrate, L-carnitine
tartrate, L-arginine alpha ketoglutarate, vitamin E (DL alpha tocopherol
acetate), fructose, zinc asparaginate, vitamin C, coenzyme Q10, orange
aroma identical to natural flavor, sweetening sucralose, vitamin B2
(riboflavin), vitamin B12 (cyanocobalamin), sweetening "Sladin 200K"
(contains: sodium saccharinate, sodium cyclamate), vitamin B6 (pyridoxine
hydrochloride), folic acid, sodium selenite.
Description and properties
Action of Apexa is determined by the properties of its active
ingredients:
1 L-carnitine tartrate:
 L-carnitine is a natural vitamin-like substance providing the entire
spermatogenesis process with energy
 L-carnitine is found in high concentrations in the epididymis and plays an
important role in metabolism and maturation of spermatozoa. It also
affects spermatozoa mobility and is an antioxidant.
 Lack of L-carnitine in the body leads to a decrease in the cellular energy
of spermatozoa, which significantly reduces the quality of sperm.
 The use of L-carnitine tartrate normalizes the balance of oxidation and
anti-oxidation processes in sperm and its fertilizing ability.
 As a whole, the effect of carnitine on the indices of the routine
spermogram is described in the literature, and in some cases its effects
on the functional characteristics of the spermatozoa have been studied.
 The concentration of L-carnitine at men with oligoasthenozoospermia is
reduced as compared with the fertile men.
 There is a significant positive correlation between LC level and the
quantity of spermatozoa, as well as their mobility.
 Clinical trials have shown that carnitine improves spermatozoa
parameters at men with astheno and oligozoospermia
 These observations, together with the firmly established role of L-
Carnitine in the production of energy by spermatozoa, provide the
scientific basis for the application of therapy for the treatment of many
cases of male infertility.
 The improvement of indices of spermogram optimizes the forecast while
conducting the auxiliary reproductive technologies. In addition, L-carnitine
can be used in the prevention and treatment of secretory male infertility.
 Vitali et al. studied the effectiveness of the oral administration of 3 g of LC
per day for 3 months for 47 patients [Vitali et al., 1995]
 Young age, infertility for at least 2 years, and idiopathic
asthenozoospermia as a cause of infertility have been the criteria of
inclusion in the given study.
 At the end of the therapeutic period, approximately 80% of patients
experienced an increase in spermatozoa mobility to a level almost equal
to the control group of 110 fertile donors and exceeding the lower WHO
standard.
 The average quantity of spermatozoa increased by 44.6% and the
average quantity of mobile spermatozoa increased by 99.6%
 A study has been conducted, whose purpose was to study the influence of
carnitine on the physical indicators of the ejaculate, as well as the
quantitative and functional characteristics of spermatozoa at men with
the oligoasthenozoospermia and the male factor of infertility in marriage.
 60 patients with idiopathic pathospermia aged 23-35 years have been
examined. The average age of patients in the group was 29.2 ± 0.8 years.
All the surveyed have been in the infertile marriage from 1 year to 10
years
 The conducted clinical study showed that L-carnitine in a form of tartrate
normalizes the balance of pro- and antioxidant systems in the ejaculate.
This leads not only to an improvement of ejaculate characteristics, but
also to an approach of pregnancy at the wives of the studied patients
(within 3 months of treatment, i.e., in the period during which the
maturation of spermatozoa is fully completed, pregnancy occurred in 14
(23%) patients).
2 Zinc asparaginate:
 Zinc is responsible for the processes of growth and production of the male
sex hormone – testosterone
 Zinc, as a biological component, is present in many organs, but its
maximum content is found in spermatozoa (up to 2 mg of zinc per
milliliter) and the prostate gland of men. This shows the great importance
of zinc for spermatogenesis and the functioning of the prostate.
 Zinc deficiency threatens men with the following:
 sexual dysfunction
 reduction of sperm quality and infertility
 decrease in the synthesis of sex hormones (testosterone)
 Zinc is used in the clinical practice at the treatment of male infertility and in
programs of auxiliary reproductive technologies.
3 Sodium Selenite:
 Selenium is an indispensable element for the normal spermatogenesis
and the provision of male fertility, regulates the functioning of the genital
organs, participates in the synthesis of testosterone.
 Selenium is one of the main micro elements of the antioxidant system of
the human body. Selenium is part of the catalytic center of the main
enzyme of the antioxidant system of glutathione peroxidase, thereby
ensuring the inactivation of active forms of oxygen that have a toxic
effect on spermatozoa, reducing the qualitative indices of ejaculate.
 In addition, the active forms of oxygen that cause oxidative stress have a
negative effect on endothelial cells. As a result conditions contributing to
the development of erectile dysfunction appear.
 Selenium is a synergist of vitamin E, thereby enhancing its antioxidant
activity.
 It is interesting that the activity of spermatozoa is greatly determined by
the presence of a specific selenium-containing protein in the tail of the
spermatozoon.
 Selenium has an antitumor effect and its lack may be a risk factor for the
development of malignant tumors of the prostate gland, ovaries.
4 Magnesium citrate:
 Magnesium refers to vital elements
 Magnesium increases fertilizing ability, as it increases the mobility of
spermatozoa.
 Magnesium increases the quantity of bioactive (free) testosterones at the
men
 An in vitro study showed that magnesium makes testosterone more
bioactive. The mineral inhibits HSPG (globulin binding sex hormones),
which binds to free testosterone, making it inaccessible to receptors and
is, in fact, useless.
 Magnesium stimulates energy production, contributes to regulate the
levels of vitamin D, potassium, calcium, copper and zinc.
 The lack of magnesium and zinc seriously decreases the level of
testosterone.
5 Vitamins C and E:
 The sufficient content of vitamins is necessary for the normal functioning
of the organism and, in particular, the sexual system. Vitamins and micro
elements with antioxidant activity are most important for the
reproductive system of men (vitamin E and C)
 A group of scientists from the Harvard University found that four out of
five couples who cannot conceive a child have a lack of vitamins C and E.
 Vitamin C directly affects sperm production and increases spermatozoa
mobility, and can help prevent spermatozoa from sticking together (it is
used to disagglutination of sperm in case of male infertility. Sperm
agglutination is caused by the increased oxidation of a number of its
proteins. In the presence of vitamin C, proteins are not oxidized,
regenerate and spermatozoa are separated, the percent of normal
spermatozoa increased, participate in the synthesis of testosterone,
contributes to the improvement of the production of healthy spermatozoa.
 Vitamin E stimulates the sexual and reproductive function, has a positive
effect on potency, improves sexual function, positively effect on
hormones, prevents the damage of spermatozoa cells, accelerates the
healing of damaged cellular structures, increases the number, mobility
and vitality of spermatozoa.
6 Vitamins B2 B6 B9 B12:
 The vitamins of group B increase testosterone synthesis, restore energy
exchange, protect the liver, improve the functioning of the heart, the
nervous system
 Vitamin B6 (pyridoxine) improves the activity and mobility of
spermatozoa, contributes to the suppression of the production of the
prolactin hormone, which is responsible for the increase of the volume of
the prostate gland, the development of benign hyperplasia and disorder
of reproductive functions. Vitamin B 6 is necessary for the synthesis of
DNA and RNA. It participates in the proper absorption and metabolism of
carnitine.
 Vitamin B9 (folic acid) participates in the formation of the structure of
spermatozoa, controls their mobility and functionality, increases the
volume of non-defective spermatozoa and the chances of conception.
 Vitamin B12 (cyanocobalamin) protects against the prostate cancer,
increases the number and mobility of spermatozoa, improves the quality
of sperm, is used for the solution of problems of infertility.
7 L-arginine:
 Stimulates spermatogenesis and blood supply to the genitals
 Favorably effects on the health of the prostate gland, increases sperm
production and increases blood flow to the genitals, creating conditions
for more stable and prolonged erection.
 Seminal fluid consists of protein building material by 80%, so a lack of L-
arginine can lead to infertility
8 Fructose:
 is the main source of energy for ejaculated spermatozoa and improves the
fertility properties of the ejaculate.
9 Coenzyme Q10:
 Coenzyme Q10 has properties identical to vitamins, but due to the fact that
it is synthesized by the body, it is not included in the number of vitamins.
Most of all it is present in mitochondria and is involved in the most important
chemical reactions.
 Coenzyme Q 10 is able to improve the quality of sperm and positively affects
the kinetic characteristics of gametes
 Researches have shown that coenzyme Q10 is able to improve sperm
density and quantity at the infertile men.
 The quality of sperm was associated with oxidative stress, and at the same
time it was assessed what level of coenzyme Q 10 could favorably affect
sperm quality. The research involved 212 infertile men, who were divided
into two groups. One group took coenzyme Q 10 (300 mg, Kaneka, Japan),
the second group took placebo for 26 weeks.
 An increase in spermatozoa density and an improvement in their motility has
been noted. The effect on the sperm quantity was also positive. The
subsequent analyzes showed an increase in the percentage of correct sperm
forms. In the group treated with coenzyme Q 10, a significant, 100%
increase in the acrosome reaction has been registered as compared with an
increase of 1% in the group taking placebo. The acrosomal reaction helps the
spermatozoon penetrate into the egg.
Special instructions
Before use, it is recommended to consult a doctor.
Biologically active substance.
Content
mg / sachet.
The daily use level in mg. Percentage from the level of daily use:
L-carnitine 900 300.01 3003
Coenzyme Q10 50 30.01 1673
Vitamin E 100 10.02 10003
Vitamin C 90 60.02 1503
Vitamin B2 3 1.62 1883
Vitamin B6 2 2.02 100
Vitamin B12 0.003 0.0012 3003
Folic acid 0.4 0.22 2003
Magnesium 400 400.02 100
Zinc 20 15.02 1333
Selenium 0.075 0.072 1073
1.An adequate level of the daily use according to the requirements of the
Eurasian Economic Community (Annex 5).
2 The recommended level of daily use in accordance with the requirements
of ТР ТС 022 (Annex 2).
3 Does not exceed the upper permissible level of daily use.
Contraindications:
Individual intolerance to the components, pregnancy, breast-feeding.
Before use, it is recommended to consult a doctor.
Method of administration
To dissolve 5 g of powder (the contents of one pack of sachet) in 200
ml of water. Adults should take by 200 ml of ready beverage 1 time per day
during meals.
Duration of use:
1 month. If necessary, the taking can be repeated in 2-3 weeks.
Storage conditions
Should be stored in a dry, dark place and out of reach of children, at a
temperature not exceeding 25 ° C and at relative air humidity not more than
75%.
Manufacturer
Manufactured by the order: the “Giga Farm” LLC, tel: +37494000264;
website: www. gigafarm.ru. Manufacturer: the “AlinaPharma” LLC, 142380,
the Moscow oblast, Chekhovsky district, village Lyubuchany, the “Institute of
Engineering Immunology” OJSC, building 3 (Russian Federation)

Apexa can be purchased from Monday to Friday from 9:30 p.m.-17:30 p.m. on the territory of the Russian Federation by calling the hotline 8-800 250 46 70 call center and +7 916 641 71 71 Viber, Whats APP, Telegram.
To purchase in the territory of the Republic of Armenia, you can call the hotline +374 94 000 265 or you can get it online.

ATTENTION!!! The delivery of Apexa is free of charge if our delivery service is available in your area.